A powerful antibiotic, allicin is an anti- fungal compound that is found in garlic. However, it does not mean that it can be found in its natural state. When it is chopped or crushed, the enzyme alliinase performs chemically thus converting it.
Allicin may not a be a very steady complex because it slowly disintegrates when it stands and is quickly damaged when cooked. Good thing about it is that it will do a large contribution medicinally, it fights artiosclerosis. It also has the ability to dissolve fats as well as an antioxidant to some extent.
Dubbed as Mother Nature’s insecticide, allicin was discovered in 1944 by Chester John Cavallito who primarily recognized its antimicrobial activity. It has a patent for its antifungal activity in test tubes. Albeit, there were no clinical test that were performed and was never developed into a commercial drug because of its absorption inability and foul smell.
There are some manufacturers who attempted to prevent its typical loss so that it would not come together only until after consumption in the hope of producing it inside the body.
It is done by measuring the additional water to garlic products that contain both alliin and alliinase to identify how much has been produced. But it then revealed that actual chemical reaction inside the body is a whole lot different as that being done in a test tube. The intestinal conditions hamper its absorption because the belly acid wrecks aliinase and intestinal fluids and depletes the amount created.
The enzyme that catalyzes the conversion of alliin called alliinase, has been discovered to be irreversibly neutralized to more than lower than pH3, an acidic environment found in the stomach.
Allicin is actually not bioavailable. There was a study conducted wherein 25 participants consumed a big portion approximately 90, 000 micograms versus crushed raw garlic of ten cloves. It showed that not a trace could be detected in both the blood and urine after 1 to 24 hours of intake.
Because of its towering reactivity, allicin was revealed to be entirely metabolized in the liver. If it could have reached the blood, it would have illustrated alterations into other compounds within five minutes. Also, in the method, it could have corrode the cells in the blood that brought about them to drop the capability in carrying oxygen.
Prior to that, allicin is quickly metabolized in the blood and tissues of human beings. It is doubtful however, if it contributes to any other actions in the body such as antithrombotic or better known as, blood thinning.